范晓娇，2012年毕业于陕西师范大学，获得学士学位。2017年毕业于中国科学技术大学，获博士学位，研究方向为结构生物学。2020年于中国科学技术大学博士后出站。2020-2021年于西安交通大学担任科研助理。2021-2025年于西安交通大学基础医学院担任副教授。2025年加入金腾川教授课题组，担任副研究员。目前采用生物化学与分子生物学、细胞生物学、生物物理和结构生物学等方法研究病毒性传染性疾病和癌症的致病机制，并进行药物研发。主持国家自然科学基金青年项目、中国博士后科学基金以及中央高校基本科研业务费专项资金等项目。
Xiaojiao Fan graduated from Shaanxi Normal University in 2012 with a bachelor's degree. She graduated from the University of Science and Technology of China in 2017 with a doctorate in structural biology. She completed her postdoctoral research at the University of Science and Technology of China in 2020. Dr. Fan served as a research assistant at Xi'an Jiaotong University from 2020 to 2021, subsequently she worked as an associate professor at the School of Basic Medical Sciences of Xi'an Jiao tong University from 2021 to 2025. In 2025, she joined TJ-lab as an associate researcher. Her current research focuses on elucidating the pathogenic mechanisms of viral infectious diseases and cancer, and to design drug, utilizing integrated methodologies spanning biochemistry & molecular biology, cell biology, biophysics and structural biology. She has secured and presided over several competitive grants, including the National Natural Science Foundation of China Youth Program, the China Postdoctoral Science Foundation, and the Fundamental Research Funds for the Central Universities.
发表论文
1. X. Fan, J. Jiang, D. Zhao, F. Chen, H. Ma, P. Smith, L. Unterholzner, T.S. Xiao, T. Jin, Structural mechanism of DNA recognition by the p204 HIN domain, Nucleic Acids Res 49(5) (2021) 2959-2972.
2. H.M. Mengist, X. Fan, T. Jin, Designing of improved drugs for COVID-19: Crystal structure of SARS-CoV-2 main protease M(pro), Signal Transduct Target Ther 5(1) (2020) 67.
3. X. Fan, Y. Wang, F. Guo, Y. Zhang, T. Jin, Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs, Int J Biol Macromol 164 (2020) 265-276.
4. X. Fan, T. Jin, Structures of RIG-I-Like Receptors and Insights into Viral RNA Sensing, Adv Exp Med Biol 1172 (2019) 157-188.
5. F. Chen, H. Ma, Y. Li, H. Wang, A. Samad, J. Zhou, L. Zhu, Y. Zhang, J. He, X. Fan, T. Jin, Screening of Nanobody Specific for Peanut Major Allergen Ara h 3 by Phage Display, J Agric Food Chem 67(40) (2019) 11219-11229.
