Shaheen Bibi, who graduated in 2019 from top top-ranked institute of Pakistan, Quaid-I-Azam University, has a Master in Philosophy degree in Biochemistry and Molecular Biology. Her research mainly focused on investigating the role of Sirtuins proteins in wound healing in diabetic mice using a natural compound as a Sirtuins activator. Afterward, she joined the National Institute of Health, Pakistan, as assistant Molecular Biologist, where she worked on molecular epidemiology of SARS-COV2, Dengue virus, and Zika Virus. Later on, in 2022, she joined TJ lab as a Ph.D. student and is now working on receptor tyrosine kinases and their role in cancer progression.
Representative Papers:
1.Bibi, S., Zeng, W., Zheng, P., Mehmandousti, S.M.M. and Jin, T., 2024. Discoidin Domain Receptor 1 as a potent therapeutic target in solid tumors. hLife.
2.Nazir, Farah, Arnaud John Kombe Kombe, Zunera Khalid, Shaheen Bibi, Hongliang Zhang, Songquan Wu, and Tengchuan Jin. "SARS-CoV-2 replication and drug discovery." Molecular and Cellular Probes 77 (2024): 101973.
3.Molecular epidemiology of dengue virus circulating during 2021 outbreak in Pakistan. Published Online:11 Jul 2023.https://doi.org/10.2217/fvl-2022-0196.
4.Umair M, Rehman Z, Haider SA, Ali Q, Hakim R, Bibi S, Salman M, Ikram A. Whole-genome sequencing of Crimean-Congo hemorrhagic fever virus circulating in Pakistan during 2022. J Med Virol. 2023 Mar;95(3):e28604. doi: 10.1002/jmv.28604. PMID: 36815488.
5.Umair M, Haider SA, Rehman Z, Jamal Z, Ali Q, Hakim R, Bibi S, Ikram A, Salman M. Genomic Characterization of Dengue Virus Outbreak in 2022 from Pakistan. Vaccines (Basel). 2023 Jan 11;11(1):163. doi: 10.3390/vaccines11010163. PMID: 36680008; PMCID: PMC9867254.
6.Bibi S, Ahmad F, Alam MR, Ansar M, Yeou KS, Wahedi HM. Lapachol-Induced Upregulation of Sirt1/Sirt3 is linked with Improved Skin Wound Healing in Alloxan-induced Diabetic Mice. Iran J Pharm Res. 2021 Summer;20(3):419-430. doi: 10.22037/ijpr.2021.112722.13914. PMID: 34903998; PMCID: PMC86536812.
7.Ahmad F, Bibi S, Kang M, Anees M, Ansar M, Alam MR, Kim SY, Wahedi HM. Naphthoquinones from Handroanthus impetiginosus promote skin wound healing through Sirt3 regulation. Iran J Basic Med Sci. 2020 Sep;23(9):1139-1145. doi: 10.22038/ijbms.2020.43706.10275. PMID: 32963735; PMCID: PMC7491501.
