CURRICULUM VITAE Tengchuan Jin, Ph.D.
金腾川
中国科学技术大学 博导、教授
合肥综合性国家科学中心大健康研究院 资深研究员、院长助理
教育部“长江学者奖励计划”特岗学者
中国科学院“百人计划”
E-mail: jint@ustc.edu.cn
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个人简介
1998年至2003年就读于中国科技大学生命科学院，2003年获生物学理学学士和工商管理学士学位。2003年至2008年就读于美国伊利诺伊理工大学(Illinois Institute of Technology)。 2008年获分子生物化学和生物物理学博士学位。于2008年获得了科学研究协会（Sigma Xi Society） 和伊利诺伊理工大学的优秀博士毕业生奖 (Sigma Xi Award)（全校每年仅1名）。从2008年至2014年期间，在美国国立卫生研究院(NIH)，国立过敏及传染病研究所 (NIAID)，先后任Postdoc Fellow和Research Fellow。2015年被聘为中国科技大学生命科学院特任研究员、博士生导师，2021年转为教授。在Nature Immunol,Immunity, Sig Trans Targ Ther, Cell Res, CMI,J Exp Med, Nature Commun, Nucleic Acids Res, Cell Dis, 等杂志发表论文200余篇,论文引用超过14 000次。2025年起，担任iNew Medicine执行主编，Allergy Medicine, Bulletin of Obstetrics & Gynecology等杂志编委。申请发明专利40余个，多项科研成果获得转化。2020年获得安徽省政府颁发的黄山友谊奖，2021年入选教育部“长江学者奖励计划”特岗学者。获得中科院战略先导项目、国家重点研发项目、国家基金委面上项目等项目支持。
主要研究方向
感染免疫机制与干预策略
肿瘤免疫与肿瘤治疗
蛋白质工程和抗体蛋白药物研发
研究关键词
Viral infection, Antibody, Nanobody, X-ray crystallography, Allergy, Host viral interaction, T-cell epitope, Inflammasome, Virology, Antibody discovery, Check point inhibitor, Vaccine, Diagnostic kits, Tumor immunology, Targeted degradation, Tumor immunology therapy, HSV, HPV, EBV, DENV, HIV
工作经历
2015 – 目前 教授、博导，中国科学技术大学
2012 – 2014 研究员（Research Fellow）, 美国国立卫生研究院
2008 - 2012 博士后, 美国国立卫生研究院
教育背景
2003 - 2008 美国伊利诺伊理工大学，分子生物化学和生物物理学博士
1998 - 2003 中国科学技术大学，生物学理学学士
1998 - 2003 中国科学技术大学，工商管理学士
发表论文 (#第一作者, *通讯作者)
1.杨芸茹，陈业恬，金腾川* (2026)。泛冠状病毒疫苗的研发策略与技术进展[J].生物学杂志
2.Yang Y, Chen Y, Hong M, Zou R, Yao J, Li E, Wang J, Ye X, Xing Y, Tang Y, Lu X, Ding C, He H, Tong D, Shang Y, Wang J, Zhao G, Huang X, Feng F, Cheng Q, Li B, Huang B, Tan W, Chiu S*, Jin T* (2026). Receptor binding domain-independent pancoronavirus vaccine design by fusion of conserved T/B Epitopes. Emerg Microbes Infect. 15(1):2631206.
3.Zhang Y, Bhardwaj SR, Carrere M, He X, Jin T, Xu Y(2026). Usage of nanobody-beta-galactosidase fusion in immunoassays and its application in detecting a peanut allergen.Food Chem (Oxf). 12:100357.
4.Fu S, Tang M, Zhao C, Chen S, Su M, Pan J, Zhang Y, Wang X, Jia W, Chu X, Chen S, Chen Y, Chen L, Jin T, Tian Z, Sun Y, Qian Y, Liu L, Wang H, Zhang H, Bai L* (2026). MAIT cell plasticity generates CD4+ MAIT cells that promote HCC progression via metabolic crosstalk with tumor cells. Cell Mol Immunol. 23(5):491-504.
5.Zhou X, Liu W, Hu J, Yao Q, Zhang F, Wu Q, Li L, Li J, Zhu L, Chen C, Zhang Q, Zhang R, Liu J, Shi C, Zhou H, Guo A, Wang J, Wang J, Hu Q, Li L, Jin T*, Zeng Z* (2026).Kupffer cell calibration of T cell responses via VSIG4-CD5 interaction promotes tumor evasion.Nat Immunol.
6.Cheng L, Wang K, Zhao Y, Xu Y, Zhang Y, Qu K, Liu Q, Xu Y, Ma K, Jin T, Chen F(2026). The dual effect of thermal processing on the allergenicity of buckwheat 13S globulin. J Sci Food Agric.
7.Cui J, Zhang X, Yang Y, Shan L, Li Y, Jiang L, Xie W, Jin T, Lang X(2026). Translation factor eIF4G2 directs CD8+ T cell lineage commitment by selectively enabling the IL-7 receptor response. iScience. 29(4):115313.
8.Liu XX, Shen X, Cui X, Chen X, Jin T, Cao HB, Lu X, Liu M, Hu LL, Chen Y, Chen XQ, Zeng Y, Gan Y, Ou-Yang X, Lei J, Liu FY, Chen F, Zou Y, Shen Y(2026). SARS-CoV-2 infection during the first trimester leads to profound immune dysregulation at the maternal-fetal interface despite limited virus detection in placental tissues. Nat Commun.
9.Wang Q, Ke X, Li E, Hong D, Cheng Z, Li H, Zhang J, Jin T, Gong R, Shu B, Chiu S(2026). Broadly neutralizing nanobodies target a defined structural pivot site on the RSV fusion protein. EMBO Mol Med.
10.Liu H, Zhang TB, Zhang FH, Sun LC, Lin D, Jin T, Zhang LJ, Huang JY, Cao MJ, Chen YL (2026). Dynamic remodeling of intramuscular structural proteins and its impact on abalone muscle quality during post-mortem cold storage. Food Chem. 506:148172.
11.Chen F, Cheng L, Xu Y, Ma K, Jin T* (2026). Thermally Stable Oleosin Is a Major, Cross-Reactive Allergen in Common Buckwheat (Fagopyrum esculentum) . J Agric Food Chem. 74(11):9786-9794.
12.Khalid Z, Khan K, Nazir F, Yao C, Mehmandousti SMM, Shang Y, Amin H, Xing Y, Pan X, Zhou S, Cheng Q, Jin T*, Zheng X* (2026). Identification and validation of hub genes involved in papillary thyroid carcinoma progression. BMC Cancer.
13.Wang M, Zhang X, Li W, Yao Y, Li E, Zhang B, Zhou J, Liu S, Gao Y, Zhu Z, Zhu L, Liu M, Hu J, Peng C, Li F, Chen M, Liu H, Yao C, Shang Y, Yan F, Gong P*, Jin T*, Chiu S* (2026). A highly potent nanobody-based bispecific therapeutic provides broad-spectrum protection against ebolavirus. Nat Commun.17(1):4040.
14.Lin X, Deng S, Li W, Vendra VPR, Yang J, Zhang X, Qin T, Xu Z, Liu M, Hejtmancik JF, Jin T*, Wang Q*(2026). βA4-Crystallin Mutations Disrupt Structural Stability and Crystallin Interactions in Congenital Cataract Pathogenesis.Invest Ophthalmol Vis Sci.67(3):29.
15.Shang G, Zheng P, Ni H, Wei S, Li L, Lei X, Wu Z, He X, Wang Z, Zhu Z, Ou H, He L, Li Z, Jin T*, Zhao G* (2026). AI-Guided Droplet Microreactors Enable Rapid and Reproducible Protein Crystallization. Small. 19:e10977.
16.Tao J, Cheng Q, Zhang P, Yu G, Chen Q, Yang M, Wu Q, Fang H, Wu H, Song X, Chen Z, Chen M, Meng X, Lei M, Jin T*(2026). ANXA1-mediated mTOR/FABP4 Inhibition Drives Antifibrotic Macrophage Reprogramming in Lupus Nephritis. Int J Biol Sci. 22(5):2343-2360.
17.Zhang J, Chang R, Zhao A, Li X, Sun Y, Zhang J, Wang R, Jin T* (2025). Pharmacokinetic considerations and strategies for antibody-based therapeutics. Drug Metab Rev. 1-32.
18.Liu ZY, Lei WH, Wan HY, Tao FY, Tao XM, Jin T, Cao MJ, Lin D, Sun LC, Zhang LJ, Chen YL* (2026). Construction and evaluation of a synthetic VNAR library for targeted antigen screening. Protein Sci. 35(1):e70423.
19.Zhang H, Jin T, Xue M, Wu S, Zheng C (2026).When glycobiology meets inflammasome activation: Insights and implications.J Adv Res.79:833-846.
20.Chen F, Xu Y, Ma K, Zhang Y, Jin T* (2026). Buckwheat allergy. Asian Pac J Allergy Immunol. 43(4):753-761.
21.Liu H, Zhang TB, Zhang FH, Sun LC, Lin D, Jin T, Zhang LJ, Huang JY, Cao MJ, Chen YL* (2026). Dynamic remodeling of intramuscular structural proteins and its impact on abalone muscle quality during post-mortem cold storage. Food Chem. 506:148172.
22.Yin L, Zhou S, Zhang H, Shang Y, Wu S*, Jin T* (2025). Cancer stem cells in personalized therapy: mechanisms, microenvironment crosstalk, and therapeutic vulnerabilities. Front Cell Dev Biol. 13:1619597.
23.Yin L, Zhou S, Zhang H, Yao C, Al-Qadhi ZTA, Shang Y, Wu S*, Jin T* (2025). Reprogramming the tumor microenvironment: synergistic mechanisms of antibody-drug conjugates and immune checkpoint inhibitors. Antib Ther. 8(3):262-274.
24.Chen Q, Liu C, Tao J, Zeng W, Zhu Z, Yao C, Shang Y, Tang J, Jin T* (2025). Insights into microbial dysbiosis and Cutibacterium acnes CAMP factor interactions in acne vulgaris. Microb Genom. 11(7):001449.
25.Li M, Xiao PP, Li WY, Zhang LJ, Chen YL, Jin T, Cao MJ* (2025). Rapid purification and characterization of angiotensin I-converting enzyme from porcine lung. Protein Expr Purif. 235:106780.
26.Yan S, Wang L, Liu D, Qin H, Du C, Chai J, Liu Y, Chen Y, Liu H, Jin T*(2025). Innovative dual-target AKT inhibitors unveiling novel mechanisms and translational potential. Bioorg Chem. 163:108774.
27.Yin L, Zhang H, Shang Y, Wu S*, Jin T* (2025). ErbB/HER family in cancer immunology: therapeutic advances and mechanisms. Drug Discov Today. 104436.
28.Yin L, Zhou S, Zhang H, Shang Y, Wu S*,Jin T* (2025). Cancer stem cells in personalized therapy: mechanisms, microenvironment crosstalk, and therapeutic vulnerabilities. Front Cell Dev Biol. 13:1619597.
29.Wang Q, Hong D, Li E, Cheng Z, Zhang J, Jin T, Chiu S*(2025). Generation of nanobodies against the F protein of respiratory syncytial virus and establishment of an indirect immunofluorescence assay. Microbiol Spectr. e0278424.
30.Zhang Y, Wu Q, Zhou Y, Cheng Q*, Jin T*(2025). hDNApipe: streamlining human genome analysis and interpretation with an intuitive and user-friendly interface.NAR Genom Bioinform. 7(2):lqaf088.
31.Zhu X, Lu J, Hu X, Jin T, Lu S, Feng F*(2025). Hierarchical progressive learning for zero-shot peptide-HLA binding prediction and automated antigenic peptide design.Cell Rep. 44(6):115763.
32.Yin L, He L, Zhang H, Shang Y, Fu C, Wu S*, Jin T* (2025). Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application.J Med Virol. 97(6):e70447.
33.Yin L, Zhang H, Shang Y, Wu S*, Jin T* (2025). NLRP3 Inflammasome: From Drug Target to Drug Discovery.Drug Discov Today. 30(6):104375.
34.Mołas A, Lis-Kuberka J, Bzikowska-Jura A, Wesołowska A, Jin T, Socha MW, Orczyk-Pawiłowicz M(2025). Lactoferrin and SIgA Concentrations in Human Milk of SARS-CoV-Infected Mothers-Polish Cohort Study. Nutrients. 17(11):1840.
35.Hu J#, Tan H#, Wang M, Deng S, Zheng P, Wang A, Guo M, Wang J, Li J, Qiu H, Yao C, Zhu Z, Hasi C, Pan D, He H, Shang Y, Zhu S*, Jin T* (2025). A potent protective bispecific nanobody targeting Herpes simplex virus gD reveals a novel epitope for antibody neutralizing. Nature Commun. 16(1):4196.
36.Zhou S, Li W, Zhao D, Zhang Q, Liu H, Jin T*, Pan Y* (2025). Synergistic approach to combating triple-negative breast cancer: DDR1-targeted antibody-drug conjugate combined with pembrolizumab. J Pharm Anal. 15(5):101100.
37.Chen YL, Su LL, Liu H, Zhang TB, Li G, Sun LC, Lin D, Jin T, Zhang LJ, Cao MJ*(2025). Synergistic effects of matrix metalloproteinases on the degradation of collagen in abalone (Haliotis discus hannai). Food Chem. 473:143111.
38.Yang Y, He XR, He SY, Lin JJ, Li FJ, Chen JL, Gu SN, Jin T, Chen GX, Liu GM (2025). Screening and Interaction Analysis of Shark-Derived Nanobodies against Crayfish Major Allergen Pro c 2.J Agric Food Chem. 73(17):10589-10602.
39.Zhou S, Hong M, Zhao D, Li W, Yuan X, Wang Y, Li H, Yang Y, Jin T*, Pan J*(2025). Reprogramming the Tumor Immune Microenvironment with ICAM-1-Targeted Antibody‒Drug Conjugates and B7-H3-CD3 Bispecific Antibodies. Adv Sci (Weinh). e2415577.
40.Lei WH, Liu ZY, Xie XX, Zhong N, Zhang LJ, Cao MJ, Lin D, Jin T, Zhang C, Chen YL* (2025). High-affinity VNARs targeting human hemoglobin: Screening, stability and binding analysis. Int J Biol Macromol. 299:140290.
41.Li WY, Chen H, Lin D, Zhang T, Chen YL, Jin T, Cao MJ*(2025). Purification, crystal structural characterization of porcine kidney dipeptidyl peptidase IV (PkDPP-IV) and its interaction with oyster derived inhibitory peptide ILAPPER. Int J Biol Macromol. 298:140047.
42.Ren D, Ye X, Chen R, Jia X, He X, Tao J, Jin T*, Wu S*, Zhang H* (2025). Activation and evasion of inflammasomes during viral and microbial infection.Cell Mol Life Sci. 82(1):56.
43.Yao Y, Yang Y, Wu Q, Liu M, Bao W, Wang Q, Cheng M, Chen Y, Yu Y, Cai Y, Zhang M, Yao J, He H, Jin C, Zheng C*, Jin T*, Tong D* (2025). Neutralizing antibody test supports booster strategy for young individuals after SARS-CoV-2 Omicron breakthrough. Eur J Med Res. 30(1):7.
44.Hong M, Liu M, Zhu F, Zhao D, Liu G, Han T, Fei C, Zeng W, Chen S, Wu Q, Li B, Wu S, Shang Y, Ma H, Zhou S, Xu S*, Jin T* (2025). FcRn-guided antigen trafficking enhances cancer vaccine efficacy. Cancer Immunol Immunother. 74(2):54.
45.Jia X, Wang J, Ren D, Zhang K, Zhang H*, Jin T*, Wu S* (2024). Impact of the gut microbiota-Th17 cell axis on inflammatory depression.Front Psychiatry. 15:1509191.
46.陈玉磊, 雷雯惠, 钟宁, 陈巧钦, 张凌晶, 金腾川, 曹敏杰* (2025)。糖尿病治疗的研究进展[J].中国病理生理杂志,41(04):757-765.
47.金腾川, 朱芳, 朱可心, 周颖* (2025)。人乳头瘤病毒感染中T细胞应答机制及基于T细胞的免疫治疗新策略[J].中国实用妇科与产科杂志,41(03):301-308.
48.钟宁, 雷雯惠, 刘祖英, 谢晓筱, 张凌晶, 金腾川, 曹敏杰, 陈玉磊* (2025)。血红蛋白驼源纳米抗体的筛选与表征[J].生物工程学报,41(04):1515-1534.
49.胡婧, 邓莎莎, 王美华, 刘梦瑶, 金腾川* (2025)。 中和性抗体在病毒性传染病治疗中的应用和展望[J].生物学杂志,42(01):1-8.
50.Huang Y, Liu M, Lu H, Ji Z, Jin T*, Shi L*(2024). Molecular genetic analysis of R124H TGFBIp in one family Avellino corneal dystrophy. Mol Vis. 30:290-297.
51.Ni K, Yin S, Hu J, Liu A, Zeng W, Jin T,Ye X* (2024). Analytical ultracentrifugation study of complex formation between like-charged glycinin and polyelectrolytes: Impact of ionic strength and chain length. Food Hydrocolloids. 157:110393.
52.Deng S, Xu Z, Hu J, Yang Y, Zhu F, Liu Z, Zhang H, Wu S*,Jin T* (2024). The molecular mechanisms of CD8+ T cell responses to SARS-CoV-2 infection mediated by TCR-pMHC interactions.Front Immunol. 15:1468456.
53.Zhao D, Liu M, Zeng W, Chen S, Bibi S, Wang M, Huang X, Zhu F, Zheng P, Gao Y, Wu Q, Zhang H, Cheng Q, Sun C, Bai L, Zhu Z, Li B, Wu S, Shang Y, Hasi C, Ma H, Zhou S*, Jin T* (2024). A bispecific antibody targeting the Ig domains of Siglec-E displays enhanced antitumor effects.Int J Biol Macromol. 281(Pt 4):136635.
54.Cheng Q#, Zhao W, Song X*, Jin T* (2024). Machine-learning and scRNA-Seq-based diagnostic and prognostic models illustrating survival and therapy response of lung adenocarcinoma. Genes Immun.25(5):356-366.
55.Nazir F#, Kombe Kombe AJ#, Khalid Z, Bibi S, Zhang H, Wu S*, Jin T* (2024). SARS-CoV-2 replication and drug discovery. Mol Cell Probes. 77:101973.
56.Bibi S, Zeng W, Zheng P, Mousavi M, Jin T* (2024).Discoidin domain receptor 1 as a potent therapeutic target in solid tumors. hLife.13(5):323-338.
57.Deng S, Xu Z, Wang M, Hu J, Liu Z, Zhu F, Zheng P, Kombe Kombe AJ, Zhang H, Wu S, Jin T* (2024). Structural insights into immune escape at killer T cell epitope by SARS CoV-2 Spike Y453F variants. J Biol Chem.300(8):107563.
58.Yan S#, Yang B#, Qin H, Du C, Liu H, Jin T* (2024). Exploring the therapeutic potential of monoclonal antibodies targeting TSLP and IgE in asthma management. Inflamm Res. 73(9):1425-1434.
59.Xu Z#, Kombe Kombe AJ#, Deng S, Zhang H, Wu S, Ruan J*, Zhou Y*, Jin T* (2024). NLRP inflammasomes in health and disease. Mol Biomed.5(1):14.
60.Zhang X, Luo F, Zhang H, Guo H, Zhou J, Li T, Chen S, Song S, Shen M, Wu Y, Gao Y, Han X, Wang Y, Hu C, Zhao X, Guo H, Zhang D, Lu Y, Wang W, Wang K, Tang N, Jin T, Ding M, Luo S, Lin C, Lu T, Lu B, Tian Y, Yang C, Cheng G, Yang H, Jin A, Ji X, Gong R, Chiu S, Huang A (2024). Prophylactic efficacy of an intranasal spray with 2 synergetic antibodies neutralizing Omicron. JCI Insight. 9(7):e171034.
61.Hu J#, Zhu LP#, Wang RQ, Zhu L, Chen F, Hou Y, Ni K, Deng S, Liu S, Ying W, Sun JL, Li H*, Jin T* (2024). Identification, Characterization, Cloning, and Cross-Reactivity of Zan b 2, a Novel Pepper Allergen of 11S Legumin. J Agric Food Chem. 72(14):8189-8199.
62.Esmat K, Jamil B, Kheder RK, Kombe Kombe AJ, Zeng W, Ma H, Jin T* (2024). Immunoglobulin A response to SARS-CoV-2 infection and immunity. Heliyon.10(1):e24031.
63.Li H#, Zhu L#, Wang RQ, Zhu L, Hu J, Chen F, Ma L, Tang R, Liu S, Ni K, Ye X, Zhang Y, Sun JL, Jin T* (2024). A new pepper allergen Zan b 1.01 of 2S albumins: Identification, cloning, characterization, and cross-reactivity.Asian Pac J Allergy Immunol.
64.王璇, 程露露, 胡婧, 马克龙, 孙安源, 金腾川, 陈凤, 徐杨书函(2024). 尘螨过敏原Der p 7新的IgE抗原表位鉴定及尘螨交叉反应性的研究[J].海南医学院学报,30(22):1697-1707.
66.Zhang C, Li Y, Samad A, He H, Ma H, Chen Y, Jin T* (2023). Kyasanur Forest disease virus NS3 helicase: Insights into structure, activity, and inhibitors. Int J Biol Macromol. 254(3):127856.
67.Kombe AJK, Zoa-Assoumou S, Bounda GA, Nsole-Biteghe FA, Jin T*, Zouré AA (2023). Advances in Etiopathological Role and Control of HPV in Cervical Cancer Oncogenesis. Front Biosci (Landmark Ed). 28(10):245.
68.Zeng W, Jia X, Chi X, Zhang X, Li E, Wu Y, Liu Y, Han J, Ni K, Ye X, Hu X, Ma H, Yu C, Chiu S, Jin T* (2023). An engineered bispecific nanobody in tetrameric secretory IgA format confers broad neutralization against SARS-CoV-1&2 and most variants. Int J Biol Macromol. 253(3):126817.
69.Nie W, Zhang R, Hu C, Jin T, Wei X, Cui H* (2023). A self-enhanced electrochemiluminescence array chip for portable label-free detection of SARS-CoV-2 nucleocapsid protein with smartphone. Biosens Bioelectron. 240:115662.
70.Wang S#, Qu F, Zhang R, Jin T, Zheng T*, Shu J*, Cui H* (2023). Emission Onset Time-Adjustable Chemiluminescent Gold Nanoparticles with Ultrastrong Emission for Smartphone-Based Immunoassay of Severe Acute Respiratory Syndrome Coronavirus 2 Antigen. Anal Chem. 95(33):12497-12504.
71.Xiang N#, Li YJ#, Liu MY, Wu QQ, Zhang YX, Jin HZ, Wang Q, Li YW, Tong DL, Xue T, Jin T*, Bao W, Chen Z* (2023). Antibody responses following the surge of SARS-CoV-2 Omicron infection among patients with systemic autoimmune rheumatic diseases. Rheumatol Adv Pract. 7(2):rkad064.
72.Chen YL#, Xie XX#, Zheng P#, Zhu C, Ma H, Khalid Z, Xie YJ, Dang YZ, Ye Y, Sheng N, Zhong N, Lei WH, Zhang C, Zhang LJ, Jin T*, Cao MJ* (2023). Selection, identification and crystal structure of shark-derived single-domain antibodies against a green fluorescent protein. Int J Biol Macromol.247:125852.
73.Li Y#, Zhang C, Samad A, Zheng P, Li Y, Chen F, Jin T* (2023). Structural mechanism of dsDNA recognition by the hMNDA HIN domain: New insights into the DNA-binding model of a PYHIN protein. Int J Biol Macromol. 245:125461.
74.Zhang Y*, Che H, Li C, Jin T (2023). Food Allergens of Plant Origin. Foods. 12(11):2232.
75.Hu S#, Wang N#, Chen S#, Zhang H#, Wang C, Ma W, Zhang X, Wu Y, Lv Y, Xue Z, Bai H, Ge S, He H, Lu W, Zhang T, Ding Y, Liu R, Han S, Zhan Y, Zhan G, Guo Z, Zhang Y, Lu J, Gao J, Jia Q, Wang Y, Wang H, Lu S, Jin T, Chiu S*, He L* (2023). Harringtonine: A more effective antagonist for Omicron variant. Biochem Pharmacol.213:115617.
76.Kombe Kombe AJ#, Jin T* (2023). Editorial: Host-microbe interaction in SARS-CoV-2 infection: mechanism and intervention. Front Immunol. 14:1198868.
77.Chen YL#, Xie XX, Zhong N, Sun LC, Lin D, Zhang LJ, Weng L, Jin T*, Cao MJ* (2023). Research Progresses and Applications of Fluorescent Protein Antibodies: A Review Focusing on Nanobodies. Int J Mol Sci. 24(5):4307.
78.Zhang H, Gao J, Tang Y, Jin T*, Tao J* (2023). Inflammasomes cross-talk with lymphocytes to connect the innate and adaptive immune response. J Adv Res. S2090-1232(23)00025-5.
79.Fu S#, Liu M#, Zhu C, Zhang H, Zhao C, Xie Y, Chen G, Sheng D, Pan J, He Z, Dai Y, Gao Y, Li X, Chen L, Qian Y, Jin T, Sun C, Tian Z, Wang H, Bai L (2023). Regulatory MAIT cells controlled by β1 adrenergic receptor signaling contribute to hepatocellular carcinoma progression. Hepatology. 78(1):72-87.
80.Chen Y, Jin T, Li M, Yun X, Huan F, Liu Q, Hu M, Wei X, Zheng P, Liu G (2023). Crystal Structure Analysis of Sarcoplasmic-Calcium-Binding Protein: An Allergen in Scylla paramamosain. J Agric Food Chem. 71(2):1214-1223.
81.舒航, 金腾川*, 王华* (2023). 盘状结构域受体1(DDR1):实体肿瘤治疗的新靶点[J].生物学杂志,40(02):1-8.
82.饶圣宏, 赵忍, 张雪薇, 金腾川* (2023). 合肥市过敏性疾病人群IgE水平筛查结果分析[J].安徽理工大学学报(自然科学版),43(02):103-108.
83.Zhang Y, Bhardwaj SR, Vilches A, Breksa A, Lyu SC, Chinthrajah S, Nadeau KC, Jin T(2022). IgE binding epitope mapping with TL1A tagged peptides. Mol Immunol. 153:194-199.
84.Shifa ul Haq H.M., Kombe Kombe AJ, Zahid A, Babar M, Zeng W, He H, Jin T* (2022).SARS-CoV-2 nucleocapsid protein: Importance in viral infection. JUSTC. 52(6): 1.
85.Tong D#, Zhang M#, Yang Y#, Xia H#, Tong H, Zhang H, Zeng W, Liu M, Wu Y, Ma H, Hu X, Liu W, Cai Y, Yao Y, Yao Y, Liu K, Shan S, Li Y, Gao G, Guo W, Peng Y, Chen S, Rao J, Zhao J, Min J, Zhu Q, Zheng Y, Liu L, Shan C, Zhong K, Qiu Z*, Jin T*, Chiu S*, Yuan Z*, Xue T* (2022). Single-dose AAV-based vaccine induces a high level of neutralizing antibodies against SARS-CoV-2 in rhesus macaques. Protein Cell. 14(1):69-73.
86.Ma H#, Zhang X#, Zeng W#, Zhou J#, Chi X, Chen S, Zheng P, Wang M, Wu Y, Zhao D, Gong F, Lin H, Sun H, Yu C, Shi Z, Hu X, Zhang H*, Jin T*, Chiu S* (2022). A bispecific nanobody dimer broadly neutralizes SARS-CoV-1 & 2 variants of concern and offers substantial protection against Omicron via low-dose intranasal administration. Cell Discov. 8(1):132.
87.Xu Z, Deng S, Huang Y, Yang Y, Sun L, Liu H, Zhao D, Zeng W, Yin X, Zheng P, Wang Y, Liu M, Zhao W, Xiao TS, Zhou Y, Jin T*(2022). The CARD8 T60 variant associates with NLRP1 and negatively regulates its activation. Front Immunol. 13:1047922.
88.Gao Y#, Wang W#, Yang Y, Zhao Q, Yang C, Jia X, Liu Y, Zhou M, Zeng W, Huang X, Chiu S, Jin T*, Wu X*(2022). Developing Next-Generation Protein-Based Vaccines Using High-Affinity Glycan Ligand-Decorated Glyconanoparticles. Adv Sci (Weinh). e2204598.
89.Chen YL, Zhang MH, Su LL, Sun LC, Qiu XJ, Lin D, Zhang LJ, Jin T*, Cao MJ* (2022). Relationships of Matrix Metalloproteinase 1 and a Tissue Inhibitor of Metalloproteinase to Collagen Metabolism in Haliotis discus hannai. J Agric Food Chem.70(47):14886-14897.
90.Kombe Kombe AJ, Biteghe FAN, Ndoutoume ZN, Jin T*(2022). CD8+ T-cell immune escape by SARS-CoV-2 variants of concern. Front Immunol. 13:962079.
91.Zhang H, Gao J, Fang W, Tang Y, Fang X, Jin T*, Tao J* (2022). Role of NINJ1 in Gout Flare and Potential as a Drug Target. J Inflamm Res. 15:5611-5620.
92.Jiang Y, Wang T, Sheng D, Han C, Xu T, Zhang P, You W, Fan W, Zhang Z, Jin T, Duan X, Yuan X, Liu X, Zhang K, Ruan K, Shi J, Guo J, Cheng A, Yang Z*(2022). Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression. J Biol Chem. 102561.
93.Chen YL#, Lin JJ#, Ma H, Zhong N, Xie XX, Yang Y, Zheng P, Zhang LJ, Jin T*, Cao MJ*(2022). Screening and Characterization of Shark-Derived VNARs against SARS-CoV-2 Spike RBD Protein. Int J Mol Sci. 23(18):10904.
94.Ma H#, Zhang X#, Zheng P#, Dube PH#, Zeng W#, Chen S#, Cheng Q, Yang Y, Wu Y, Zhou J, Hu X, Xiang Y*, Zhang H*, Chiu S*, Jin T*(2022). Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron. Cell Res. 32(9):831-842.
95.Zhang X, Zhang H, Li T, Chen S, Luo F, Zhou J, Zheng P, Song S, Wu Y, Jin T, Tang N, Jin A, Yang C, Cheng G, Gong R, Chiu S*, Huang A*(2022). A potent neutralizing antibody provides protection against SARS-CoV-2 Omicron and Delta variants via nasal delivery. Signal Transduct Target Ther. 7(1):301.
96.Khalid Z, Huan M, Sohail Raza M, Abbas M, Naz Z, Kombe Kombe AJ, Zeng W, He H, Jin T*(2022). Identification of Novel Therapeutic Candidates Against SARS-CoV-2 Infections: An Application of RNA Sequencing Toward mRNA Based Nanotherapeutics. Front Microbiol. 13:901848.
97.Cao X#, Liu K#, Yan S, Li S, Li Y, Jin T*, Liu S* (2022).Mechanical regulation of the helicase activity of Zika virus NS3. Biophys J. S0006-3495(22)00603-8.
98.Li Y, Zheng P, Liu T, Shi C, Wang B, Xu Y, Jin T* (2022). Structural Requirements and Plasticity of Receptor-Binding Domain in Human Coronavirus Spike. Front Mol Biosci. 9:930931.
99.Xu S, Jin T*, Weng J* (2022). Endothelial Cells as a Key Cell Type for Innate Immunity: A Focused Review on RIG-I Signaling Pathway. Front Immunol. 13:951614.
100.Cong M#, Yang Y#, Tong H, Shimu AS, Wang B, Li Q, Li F, Yang Y, Jin T*, Li B* （2022). 3-dose of RBD vaccine is sufficient to elicit a long-lasting memory response against SARS-CoV-2 infection. Signal Transduct Target Ther. 7(1):84.
101.Fan X, Jiao L, Jin T* (2022). Activation and Immune Regulation Mechanisms of PYHIN Family During Microbial Infection. Front Microbiol. 12:809412.
102.Zou J, Li L, Zheng P, Liang W, Hu S, Zhou S, Wang Y, Zhao J, Yuan D, Liu L, Wu D, Xu M, Zhang F, Zhu M, Wu Z, Cao X, Ni M, Ling X, Wu Y, Kuang Z, Hu M, Li J, Li X, Guo X, Xu T, Jiang H, Gao C, Yu M, Liu J, Zhong N, Zhou J*, Huang JA*, Jin T*, He J* (2022). Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance. J Clin Invest. 132(4):e154987.
103.Khalid Z, Chen Y, Yu D, Abbas M, Huan M, Naz Z, Mengist HM, Cao MJ*, Jin T* (2022). IgNAR antibody: Structural features, diversity and applications. Fish Shellfish Immunol. 121:467-477.
104.He XR, Yang Y, Kang S, Chen YX, Zheng PY, Chen GX, Chen XM, Cao MJ,Jin T*, Liu GM*(2022). Crystal Structure Analysis and IgE Epitope Mapping of Allergic Predominant Region in Scylla paramamosain Filamin C, Scy p 9. J Agric Food Chem. 70(4):1282-1292.
105.Kombe Kombe AJ, Xie J, Zahid A, Ma H, Xu G, Deng Y, Nsole Biteghe FA, Mohammed A, Dan Z, Yang Y, Feng C, Zeng W, Chang R, Zhu K, Zhang S, Jin T* (2022). Detection of Circulating VZV-Glycoprotein E-Specific Antibodies by Chemiluminescent Immunoassay (CLIA) for Varicella-Zoster Diagnosis. Pathogens. 11(1):66.
106.陈玉磊, 林锦锦, 郑培义, 曹敏杰*, 金腾川* (2022). 新冠病毒中和单克隆抗体及纳米抗体研究进展[J].生物工程学报,38(09):3173-3193.
107.邓莎莎, 徐志豪, 胡婧, 金腾川* (2022). 新型冠状病毒T细胞免疫的人群特征[J].生物学杂志,39(03):24-29.
108.林榕榕, 陈玉磊, 金腾川*, 曹敏杰* (2022). B淋巴细胞活化因子抗体在自身免疫性疾病治疗中的研究进展[J].生物工程学报,38(03):903-914.
109.Zhang C, Li Y, Samad A, Zheng P, Ji Z, Chen F, Zhang H, Jin T* (2021). Structure and mutation analysis of the hexameric P4 from Pseudomonas aeruginosa phage phiYY. Int J Biol Macromol. S0141-8130(21)02534-4.
110.Mengist HM, Kombe Kombe AJ, Mekonnen D, Abebaw A, Getachew M, Jin T* (2021). Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity. Semin Immunol.55:101533.
111.Zahid A, Ismail H, Jin T* (2021). Molecular and structural aspects of gasdermin family pores and insights into gasdermin-elicited programmed cell death. Biochem Soc Trans.49(6):2697-2710.
112.Shi C, Lv D, Zhou K, Jin T, Wang G, Wang B, Li Y, Xu Y* (2021). Clinical and Laboratory Characteristics of Patients infected by Listeria monocytogenes at a Tertiary Hospital in Hefei City, China. Infect Drug Resist. 14:4409-4419.
113.Mohammed A, Zeng W, Mengist HM, Kombe Kombe AJ, Ou H, Yang Y, Dan Z, Xu Z, Ma H*, Jin T* (2021). Generation, biochemical characterizations and validation of potent nanobodies derived from alpaca specific for human receptor of advanced glycation end product. Biochem Biophys Res Commun. 581:38-45.
114.Wang S, Shu J, Lyu A, Huang X, Zeng W, Jin T*, Cui H*(2021). Label-Free Immunoassay for Sensitive and Rapid Detection of the SARS-CoV-2 Antigen Based on Functionalized Magnetic Nanobeads with Chemiluminescence and Immunoactivity. Anal Chem. 93(42):14238-14246.
115.Mekonnen D, Mengist HM, Jin T*(2021). SARS-CoV-2 subunit vaccine adjuvants and their signaling pathways. Expert Rev Vaccines.21(1):69-81.
116.Lyu A, Jin T, Wang S, Huang X, Zeng W, Yang R, Cui H*(2021). Automatic label-free immunoassay with high sensitivity for rapid detection of SARS-CoV-2 nucleocapsid protein based on chemiluminescent magnetic beads. Sens Actuators B Chem. 349:130739.
117.Zhang H, Deng S, Ren L, Zheng P, Hu X, Jin T*, Tan X*(2021). Profiling CD8 + T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants. Cell Rep. 36(11):109708.
118.Xie J, Ding C, He J, Zhang Y, Ni S, Zhang X, Chen Q, Wang J, Huang L, He H, Li W, Ma H, Jin T*, Zhang S*, Gao Y* (2021). Novel Monoclonal Antibodies and Recombined Antibodies Against Variant SARS-CoV-2. Front Immunol. 12:715464.
119.Zhang Z, Zhang G, Guo M, Tao W, Liu X, Wei H, Jin T, Zhang Y, Zhu S (2021). The Potential Role of an Aberrant Mucosal Immune Response to SARS-CoV-2 in the Pathogenesis of IgA Nephropathy. Pathogens. 10(7):881.
120.Li S, Wang L, Xu Z, Huang Y, Xue R, Yue T, Xu L, Gong F, Bai S, Wu Q, Liu J, Lin B, Zhang H, Xue Y, Xu P, Hou J, Yang X, Jin T, Zhou R, Lou J, Xu T, Bai L (2021). ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation. J Exp Med. 218(9):e20202637.
121.Shi C, Wang L, Lv D, Wang G, Mengist HM, Jin T, Wang B, Huang Y, Li Y, Xu Y (2021). Epidemiological, Clinical and Laboratory Characteristics of Patients with Brucella Infection in Anhui Province, China. Infect Drug Resist. 14:2741-2752.
122.Gong F, Wei HX, Qi J, Ma H, Liu L, Weng J, Zheng X, Li Q, Zhao D, Fang H, Liu L, He H, Ma C, Han J, Sun A, Wang B, Jin T*, Li B*, Li B* (2021). Pulling-Force Spinning Top for Serum Separation Combined with Paper-Based Microfluidic Devices in COVID-19 ELISA Diagnosis. ACS Sens. 6(7):2709-2719.
123.Tao W, Zhang G, Wang X, Guo M, Zeng W, Xu Z, Cao D, Pan A, Wang Y, Zhang K, Ma X, Chen Z, Jin T, Liu L, Weng J, Zhu S (2021). Analysis of the intestinal microbiota in COVID-19 patients and its correlation with the inflammatory factor IL-18.Med Microecol. 5:100023.
124.Kombe Kombe AJ, Zahid A, Mohammed A, Shi R, Jin T* (2021). Potent Molecular Feature-based Neutralizing Monoclonal Antibodies as Promising Therapeutics Against SARS-CoV-2 Infection. Front Mol Biosci. 8:670815.
125.Chen F, Li H, Fan X, Li Y, Zhang C, Zhu L, Hu J, Kombe Kombe AJ, Xie J, Yin D, Zhang Y, Sun JL, Tang R*, Jin T* (2021). Identification of a Novel Major Allergen in Buckwheat Seeds: Fag t 6. J Agric Food Chem.69(45):13315-13322.
126.Mengist HM, Dilnessa T, Jin T* (2021).Structural Basis of Potential Inhibitors Targeting SARS-CoV-2 Main Protease. Front Chem. 9:622898.
127.Lin B, Torreggiani S, Kahle D, Rumsey DG, Wright BL, Montes-Cano MA, Silveira LF, Alehashemi S, Mitchell J, Aue AG, Ji Z, Jin T, de Jesus AA, Goldbach-Mansky R (2021). Case Report: Novel SAVI-Causing Variants in STING1 Expand the Clinical Disease Spectrum and Suggest a Refined Model of STING Activation. Front Immunol. 12:636225.
128.Zhu C, Xu Z, Zhang T, Qian L, Xiao W, Wei H, Jin T*, Zhou Y* (2021). Updates on Pathogenesis, Diagnostic and Therapeutic Perspectives for Ovarian Clear Cell Carcinoma. J Cancer. 12(8):2295-2316.
129.Ma H, Zeng W, Meng X, Huang X, Yang Y, Zhao D, Zhou P, Wang X, Zhao C, Sun Y, Wang P, Ou H, Hu X, Xiang Y, Jin T*(2021). Potent Neutralization of SARS-CoV-2 by Hetero-bivalent Alpaca Nanobodies Targeting the Spike Receptor-Binding Domain. J Virol. 95(10):e02438-20.
130.Fan X, Jiang J, Zhao D, Chen F, Ma H, Smith P, Unterholzner L, Xiao T.S, Jin T* (2021). Structural mechanism of DNA recognition by the p204 HIN domain. Nucleic Acids Res. 49(5):2959-2972.
131.Mengist HM, Mekonnen D, Mohammed A, Shi R*, Jin T*(2021). Potency, Safety, and Pharmacokinetic Profiles of Potential Inhibitors Targeting SARS-CoV-2 Main Protease. Front Pharmacol. 11:630500.
132.Li Y, Li Y, Mengist HM, Shi C, Zhang C, Wang B, Li T, Huang Y, Xu Y*, Jin T*(2021). Structural Basis of the Pore-Forming Toxin/Membrane Interaction. Toxins (Basel). 13(2):128.
133.Kombe Kombe AJ, Li B, Zahid A, Mengist HM, Bounda GA, Zhou Y, Jin T* (2021). Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation. Front Public Health. 8.
134.Zeng W#, Ma H#, Ding C#, Yang Y, Sun Y, Huang X, He W, Xiang Y, Yong G*, Jin T* (2021). Characterization of SARS-CoV-2 Specific Antibodies in COVID-19 Patients Reveals Highly Potent Neutralizing IgA. Signal Transduct Target Ther. 6(1):35.
135.Xu Z, Zhou Y, Liu M, Ma H, Sun L, Zahid A, Chen Y, Zhou R, Cao M, Wu D, Zhao W, Li B*, Jin T*(2021). Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome CARD-CARD is critical for NLRP1 activation. Cell Death and Disease. 12(1):57.
136.Chen YY, Li MS, Yun X, Xia F, Hu MJ, Jin T, Cao MJ, Lai D, Chen G, Liu GM *(2021).Site-Directed Mutations of Calcium-Binding Sites Contribute to Reducing the Immunoreactivity of the EF-Hand Sarcoplasmic Calcium-Binding Protein in Scylla paramamosain. J Agric Food Chem. 69(1):428-436.
137.Zhang H, Zahid A, Ismail H, Tang Y,Jin T*, Tao J* (2021). An Overview of Disease Models for NLRP3 Inflammasome Over-activation.Expert Opin Drug Discov. 21:1-18.
138.Zahid A, Ismail H, Li B*, Jin T*(2020), Molecular and Structural Basis of Cytosolic DNA Sensors in Antiviral Innate Immunity. Frontiers in Immunology. 11:613039.
139.Weber ANR*, Bittner Z, Shankar S, Liu X, Chang T, Jin T, Tapia-Abellan A (2020). Recent insights into the regulatory networks of NLRP3 inflammasome activation (2020). J Cell Sci. 133(23):jcs248344.
140.Mekonnen D#, Mengist HM#, Derbie A, Nibret E, Munshea A, He H, Li B*, Jin T* (2020). Diagnostic accuracy of serological tests and kinetics of SARS-COV-2 antibody: A systematic review and meta-Analysis. Reviews In Med Virology. e2181.
141.Liu M, Zhou K, Xu Z, Ma H, Cao X, Yin X, Zeng W, Zahid A, Fu S, Ni K, Ye X, Zhou Y, Bai L, Zhou R, Jin T*(2020). Crystal Structure of Caspase-11 CARD Provides Insights into Caspase-11 Activation. Cell Discovery. 6:70.
142.Zheng X, Luo S, Sun Y, Han M, Liu J, Sun L, Zhang L, Ling P, Ding Y,Jin T, Liu Z, Weng J*(2020). Asymptomatic patients and asymptomatic phases of Coronavirus Disease 2019 (COVID-19): a population-based surveillance study. Natl Sci Rev. 2020 Jun 23;7(10):1527-1539.
143.Tao W, Wang X, Zhang G, Guo M, Ma H, Zhao D, Sun Y, He J, Liu L, Zhang K, Wang Y, Weng J, Ma X*, Jin T*, Zhu S* (2020). Re-detectable positive SARS-CoV-2 RNA tests in patients who recovered from COVID-19 with intestinal infection. Protein & Cell. 12(3):230-235.
144.Xue M, Zhang T, Hu H, Huang Z, Zhen Y, Liang Y, Zeng Y,Jin T, Zhou L, Zhang XD*, Sun B*(2020). Predictive effects of IgA and IgG combination to assess pulmonary exudation progression in COVID-19 patients. J Med Virol. 93(3):1443-1448.
145.Ma H#, Zhao D#, Zeng W#, Yang Y, Hu X, Zhou P, Weng J, Cheng L, Zheng X*, Jin T* (2020). Decline of SARS-CoV-2-specific IgG, IgM and IgA in convalescent COVID-19 patients within 100 days after hospital discharge. Sci. China Life Sci. 28:1-4.
146.Gong F, Dai Y, Zheng T, Cheng L, Zhao D, Wang H, Liu M, Pei H,Jin T, Yu D, Zhou P* (2020). Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals. J Clin Invest. 130(12):6588-6599.
147.Zhang Y, Cheng K, Xu B, Shi J, Qiang J, Shi S, Yi Y, Li H,Jin T, Guo R, Wu Y, Liu Z, Wei X, Huang JA, Yang XH* (2020). Epigenetic Input Dictates the Threshold of Targeting of the Integrin-Dependent Pathway in Non-small Cell Lung Cancer. Front Cell Dev Biol. 8:652.
148.Guo C#, Li B#, Ma H, Wang X, Cai P, Yu Q, Zhu L, Jin L, Jiang C, Fang J, Liu Q, Zong D, Zhang W, Lu Y, Li K, Gao X, Fu B, Liu L, Ma X, Weng J, Wei H,Jin T*, Lin J*, Qu K* (2020).Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm. Nat Commun.11(1):3924.
149.Li WY, Li Y, Chen YL, Hu JJ, Mengist HM, Liu GM,Jin T*, Cao MJ*(2020). Characterization and crystal structure of prolyl endopeptidase from abalone (Haliotis discus hannai).Food Chem. 333:127452.
150.Li Y, Hu X, Tu Y, Wu T, Wang B, Ma H, Zeng W, Zhao D, Mengist HM, Kombe AJK, Zheng M, Xu Y*, Jin T*(2020). A low viral dose in COVID-19 patient: A case report. Frontiers in Public Health. 8:339.
151.Fan X, Wang Y, Guo F, Zhang Y,Jin T* (2020). Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int J Biol Macromol. 164:265-276. S0141-8130(20)33812-5.
152.Ma H#, Zeng W#, He H#, Zhao D, Jiang D, Zhou P, Cheng L, Li Y*, Ma X*,Jin T*(2020). Serum IgA, IgM, and IgG responses in COVID-19. Cell Mol Immunol. 17(7):773-775.
153.Zeng W, Liu G, Ma H, Zhao D, Yang Y, Liu M, Mohammed A, Zhao C, Yang Y, Xie J, Ding C, Ma X, Weng J, Gao Y, He H*,Jin T*(2020). Biochemical characterization of SARS-CoV-2 nucleocapsid protein. Biochem Biophys Res Commun. 527(3):618-623.
154.Mengist HM, Fan X,Jin T*(2020). Designing of improved drugs for COVID-19: Crystal structure of SARS-CoV-2 main protease Mpro.Signal Transduct Target Ther. 5(1):67.
155.Huang Y, Wang H, Hao Y, Lin H, Dong M, Ye J, Song L, Wang Y, Li Q, Shan B, Jiang Y, Li H, Shao Z, Kroemer G, Zhang H, Bai L,Jin T, Wang C, Ma Y, Cai Y, Ding C, Liu S, Pan Y, Jiang W*, Zhou R*(2020). Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity. Nat Cell Biol. 22(6):716-727.
156.Han R, Hensley PJ, Li J, Zhang Y, Stark TW, Heller A, Qian H, Shi J, Liu Z, Huang JA,Jin T, Wei X, Zhou BP, Wu Y, Kyprianou N, Chen J, Yang XH*(2020). Integrin-associated CD151 is a suppressor of prostate cancer progression. Am J Transl Res. 12(4):1428-1442.
157.Xie J, Ding C, Li J, Wang Y, Guo H, Lu Z, Wang J, Zheng C, Jin T, Gao Y, He H (2020). Characteristics of Patients with Coronavirus Disease (COVID-19) Confirmed using an IgM-IgG Antibody Test. J Med Virol. 164:265-276.
158.Zhang Y, Jin T (2020). Almond allergens: update and perspective on identification and characterization. J Sci Food Agric. 100(13):4657-4663.
159.Zhang Z, Jin T, Xie X, Ban X, Li C, Hong Y, Cheng L, Gu Z, Li Z (2019). Structure of maltotetraose-forming amylase from Pseudomonas saccharophila STB07 provides insights into its product specificity.Int J Biol Macromol. 154:1303-1313.
160.Zahid A, Li B, Kombe AJK, Jin T*, Tao J* (2019). Pharmacological Inhibitors of the NLRP3 Inflammasome. 18. Front Immunol. 10:2538.
161.Zeng W, Ma H, Fan W, Yang Y, Zhang C, Arnaud Kombe Kombe J, Fan X, Zhang Y, Dong Z, Shen Z, Zhou Y, Yang M*, Jin T*(2019). Structure determination of CAMP factor of Mobiluncus curtisii and insights into structural dynamics. Int J Biol Macromol. 150:1027-1036.
162.Xia F, Li MS, Liu Q, Liu M, Yang Y, Cao MJ, Chen G, Jin T*, Liu GM* (2019). Crystal structure analysis and conformational epitope mutation of triosephosphate isomerase, a mud crab allergen.J Agric Food Chem.67(46):12918-12926.
163.Fan X, Jin T* (2019). Structures of RIG-I-Like Receptors and Insights into Viral RNA Sensing.Adv Exp Med Biol. 1172:157-188.
164.Samad A, Li Y, Zhang C, Chen F, Zeng W, Fan X, Jin T* (2019). X-ray crystal structure of putative transcription regulator lmo2088 from Listeria monocytogenes. Biochem Biophys Res Commun. 520(2):434-440.
165.Liu X, Zhao Y, Shi H, Zhang Y, Yin X, Liu M, Zhang H, He Y, Lu B, Jin T, Li F*. Human immunoglobulin G hinge regulates agonistic anti-CD40 immunostimulatory and antitumour activities through biophysical flexibility (2019). Nat Commun. 10(1):4206.
166.Chen F, Ma H, Li Y, Wang H, Samad A, Zhou J, Zhu L, Zhang Y, He J, Fan X*, Jin T* (2019). Screening of Nanobody Specific for Peanut Major Allergen Ara h 3 by Phage Display. J Agric Food Chem.67(40):11219-11229.
167.Li Y, Zeng W, Li Y, Fan W, Ma H, Fan X, Jiang J, Brefo-Mensah E, Zhang Y, Yang M, Dong Z, Palmer M, Jin T* (2019). Structure determination of the CAMP factor of Streptococcus agalactiae with the aid of an MBP tag and insights into membrane-surface attachment. Acta Cryst D. 75(Pt 8):772-781.
168.Xie X, Li Y, Ban X, Zhang Z, Gu Z, Li C, Hong Y, Cheng L, Jin T*, Li Z* (2019). Crystal structure of a maltooligosaccharide-forming amylase from Bacillus stearothermophilus STB04. Int J Biol Macromol. 138:394-402.
169.Che H, Zhang Y, Jiang S, Jin T, Lyu SC, Nadeau KC, McHugh T (2019). Almond (Prunus dulcis) allergen Pru du 8, the first member of a new family of food allergens. J Agric Food Chem.67(31):8626-8631.
170.Li W, Ji Q, Wei Z, Chen YL, Zhang Z, Yin X, Aghmiuni SK, Liu M, Chen W, Shi L, Chen Q, Du X, Yu L, Cao MJ, Wang Z, Huang S, Jin T*, Wang Q* (2019). Biochemical characterization of G64W mutant of acidic beta-crystallin 4.Exp Eye Res. 186:107712.
171.Yin X, Li W, Ma H, Zeng W, Peng C, Li Y, Liu M, Chen Q, Zhou R, Jin T* (2019). Crystal structure and activation mechanism of DR3 death domain. FEBS J. 286(13):2593-2610.
172.Duan GF, Ye Y, Xu S, Tao W, Zhao S, Jin T, Nicoll RA, Shi YS*, Sheng N* (2018). Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino-terminal domain. Nat Commun. 9(1):4879.
173.Chen YL, Li WY, Hu JJ, Li Y, Liu GM, Jin T*, Cao MJ* (2019). Nucleus-translocated matrix metalloprotease 1 regulates innate immune response in Pacific abalone (Haliotis discus hannai). Fish Shellfish Immunol. 84:290-298.
174.Yang Y, Hu MJ, Jin T, Zhang YX, Liu GY, Li YB, Zhang ML, Cao MJ, Su WJ, Liu GM* (2019). A comprehensive analysis of the allergenicity and IgE epitopes of myosinogen allergens in Scylla paramamosain. Clin Exp Allergy. 49(1):108-119.
175.Yang Y, Liu GY, Yang H, Hu MJ, Cao MJ, Su WJ, Jin T*, Liu GM * (2019). Crystal structure determination of Scylla paramamosain arginine kinase, an allergen that may cause cross-reactivity among invertebrates. Food Chem. 271:597-605.
176.Yang RQ, Chen YL, Chen F, Wang H, Zhang Q, Liu GM, Jin T*, Cao MJ* (2018).Purification, Characterization, and Crystal Structure of Parvalbumins, the Major Allergens in Mustelus griseus.J Agric Food Chem. 66(30):8150-8159.
177.Yan LJ, Jin T, Chen YL, Zhan CL, Zhang LJ, Weng L, Liu GM, Cao MJ* (2018). Characterization of a recombinant matrix metalloproteinase-2 from sea cucumber (Stichopus japonicas) and its application to prepare bioactive collagen hydrolysate. Process Biochem. 72:63-70.
178.Jin T*,＃, Brefo. E＃, Fan W, Zeng W, Li Y, Zhang YZ, Palmer M (2018). Crystal structure of the Streptococcus agalactiae CAMP factor provides insights into its membrane-permeabilizing activity. J Biol Chem. 293(30):11867-11877.
179.Li Y, Huang Y, Cao X, Yin X, Jin X, Liu S, Jiang J, Jiang W, Xiao TS, Zhou R, Cai G, Hu B, Jin T* (2018). Functional and Structural Characterization of Zebrafish ASC.FEBS J. 285(14):2691-2707.
180.Fang K, Li Y, Yin X, Samad A, Jin T* (2018).High-Level Prokaryotic Expression and Purification of Death Domain Superfamily with MBP Tag.Clin Lab. 64(4):467-475.
181.Zhou K, Fan X, Li Y, Zhang C, Jin T* (2018). High-resolution crystal structure of Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase.Acta Crystallogr F Struct Biol Commun. 74(Pt 4):236-244.
182.Jin T*, Huang M, Jiang J, Smith P, Xiao TS* (2018). Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction. PLoS One. 13(1): e0190547.
183.Hu JJ, Chen YL, Duan XK, Jin T, Li Y, Zhang LJ, Liu GM, Cao MJ* (2018). Involvement of clip-domain serine protease in the anti-Vibrio immune response of abalone (Haliotis discus hannai)-Molecular cloning, characterization and functional analysis. Fish Shellfish Immunol. 72:210-219.
184.Gong T, Yang Y, Jin T, Jiang W, Zhou R* (2018). Orchestration of NLRP3 Inflammasome Activation by Ion Fluxes. Trends Immunol. 39(5):393-406.
185.Jin T*, Wang C, Zhang CY, Wang Y, Chen YW, Guo F, Howard A, Cao MJ, Fu TJ, McHugh TH, Zhang YZ* (2017). Crystal Structure of Cocosin, A Potential Food Allergen from Coconut (Cocos nucifera). J Agric Food Chem. 65(34): 7560-7568.
186.Jiang H, He H, Chen Y, Huang W, Cheng J, Ye J, Wang A, Tao J, Wang C, Liu Q, Jin T, Jiang W, Deng X, Zhou R* (2017). Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. J Exp Med. 214(11): 3219-3238.
187.Lang X, Tang T,Jin T, Ding C, Zhou R, Jiang W(2017). TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity. J Exp Med. 214(2): 459-473.
188.Jin T*, Chuenchor W, Jiang J, Cheng J, Li YJ, Fang K, Huang M, Smith P, Xiao TS* (2017). Design of an expression system to enhance MBP-mediated crystallization. Sci Rep. 7:40991-40997.
189.Cao X#, Li YJ#*, Jin X, Li YL, Guo F, Jin T* (2017). Molecular Mechanism of Divalent-Metal-Induced Activation of NS3 Helicase and Insights into Zika Virus Inhibitor Design. Nucleic Acids Res. 44(21): 10505-10514.
190.Zhang C, Feng T, Cheng J, Li YJ, Yin X, Zeng W, Jin X, Li YL, Guo F and Jin T* (2017). Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design. Biochem Biophs Res Commun.492(4):624-630.
191.Li YJ, Li YL, Cao X, Jin X, and Jin T* (2017). Pattern recognition receptors in zebrafish provide functional and evolutionary insight into innate immune signaling pathways. Cell Mol Immunol. 14(1):80-89.
192.Zhao Y#, Cai Q#, Jin T, Zhang L, Fei D, Liu G, and Cao M (2017). Effect of Maillard reaction on the structural and immunological properties of recombinant silver carp parvalbumin. LWT Food Sci Technol. 75: 25-33.
193.江永亮, 金腾川, 陈宇星, 周丛照(2017). 革兰氏阳性病原菌表面毒力因子及其宿主识别机制[J].中国科学:生命科学,47(01):98-107.
194.Balinsky CA, Schmeisser H, Wells AI, Ganesan S, Jin T, Singh K, Zoon KC (2016). IRAV (FLJ11286), an Interferon Stimulated Gene with Antiviral Activity Against Dengue Virus, Interacts with MOV10.J Virol. 91(5).
195.Bertheloot D, Naumovski AL, Langhoff P, Horvath GL, Jin T, Xiao TS, Garbi N, Agrawal S, Kolbeck R, Latz E (2016). RAGE Enhances TLR Responses through Binding and Internalization of RNA.J Immunol. 197(10): 4118-4126.
196.Herzner A#, Hagmann CA#, Goldeck M, Keßels S, Kübler K, Wittmann S, Gramberg T, Andreeva L, Hopfner K, Mertens C, Zillinger T, Jin T, Xiao TS, Bartok E, Coch C, Ackermann D, Hornung V, Ludwig J, Barchet W, Hartmann G* and Schlee M* (2015). Sequence-specific activation of cGAS by Y-form DNA structures as found in primary HIV-1 cDNA. Nat Immunology. 16(10): 1025-33.
197.Jin T* and Xiao TS* (2015). Activation and assembly of the inflammasomes through conserved protein domain families. Apoptosis. 20(2): 151-6.
198.Jin T*, Wang Y, Chen YW, Albillos SM, Kothary MH, Fu TJ, Tankersley B, McHugh TH, Zhang YZ* (2014). Isolation and characterization of Korean pine (Pinus koraiensis) convicilin. Plant Physiol Biochem. 80: 97-104.
199.Chuenchor W#, Jin T#, Ravilious G, Xiao TS* (2014). Structures of pattern recognition receptors reveal molecular mechanisms of autoinhibition, ligand recognition and oligomerization. Curr Opin Immunol. 26:14-20.
200.Jin T*, Wang Y, Chen YW, Fu TJ, Kothary MH, McHugh TH, Zhang YZ* (2013). Crystal structure of the Korean pine (Pinus koraiensis) 7S seed storage protein with copper ligand. J Agric Food Chem. 62(1): 222-228.
201.Jakobsen MR, Andersen A, Berg RK, Bak RO, Jin T, Hansen K, Jen SB, Østergaard LJ, Towers GJ, Fitzgerald KA, Xiao TS, Mikkelsen JG, Mogensen TH, Paludan SR (2013).IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication. Proc Natl Acad Sci U S A. 110(48): E4571-4580.
202.Sirois CM#, Jin T#, Miller AL, Nakamura H, Horvath GL, Mian A, Jiang J, Schrum J, Brewah Y, Tian J, Chang C, Schowdhury PS, Sims GP, Kolbeck R, Coyle AJ, Humbles AA, Xiao TS*, Latz E * (2013). RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J Exp Med. 210: 2447-2463.
203.Jin T, Huang Mo, Smith P, Jiang J and Xiao TS (2013). Crystal structure of the caspase recruitment domain from a zebrafish guanylate-binding protein. Acta Crystallogr Sect F Struct Biol Cryst Commun. 69: 855-860.
204.Jin T, Curry J, Smith P, Jiang J, and Xiao TS (2013). Structure of the NLRP1 caspase recruitment domain reveals potential mechanisms of association with Caspase-1. Proteins. 81(7): 1266-70.
205.Jin T, Perry A, Smith P, Jiang J and Xiao TS (2013). Structure of the AIM2 pyrin domain provides insights into the mechanisms of AIM2 autoinhibition and inflammasome assembly. J Biol Chem.288: 13225-13235.
206.Jin T, Huang Mo, Smith P, Jiang J and Xiao TS (2013). Potential mechanisms for CARD8 association with procaspase-1 revealed by the crystal structure of the CARD8 caspase recruitment domain. Acta Crystallogr Sect F Struct Biol Cryst Commun. 69: 482-486.
207.Conlon J#, Burdette DL#, Sharma S, Bhat N, Jiang Z, Jin T, Xiao TS, Vogel S, Vance RE and Fitzgerald KA (2013). Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-Dimethylxanthenone-4-Acetic Acid. J Immunol. 190: 5216-5225.
208.Jin T, Guo F, Wang Y, Zhang YZ (2013). High-resolution crystal structure of human Dim2/TXNL4B.Acta Crystallogr Sect F Struct Biol Cryst Commun. 69: 223-227.
209.Jin T, Perry A, Jiang J, Smith P, Curry JA, Unterholzner L, Jiang Z, Horvath G, Rathinam V, Hornung V, Johnstone RW, Latz E, Bowie AG, Fitzgerald KA, Xiao TS (2012). Structures of The HIN domain:DNA complexes reveal ligand binding and activation mechanisms of The AIM2 inflammasome and IFI16. Immunity. 36(4): 561-571.
210.Unterholzner L, Keating SE, Baran M, Horan KA, Jensen SB, Sharma S, Sirois CM, Jin T, Latz E, Xiao TS, Fitzgerald KA, Paludan SR, Bowie AG (2010). IFI16 is an innate immune sensor for intracellular DNA. Nat Immunol. 11: 997-1004.
211.Jin T, Guo F, Chen YW, Howard A, Zhang YZ (2009). Crystal structure of Ara h 3, a major allergen in peanut. Mol Immunol. 46: 1796-1804.
212.Jin T, Albillos SM, Guo F, Howard A, Fu TJ, Kothary MH, Zhang YZ (2009). Crystal structure of prunin-1, a major component of the almond (Prunus dulcis) allergen amandin. J Agric Food Chem. 57: 8643-8651.
213.Jin T, Chen YW, Howard A, Zhang YZ (2008). Purification, crystallization and initial crystallographic characterization of the Ginkgo biloba 11S seed globulin ginnacin. Acta Crystallogr Sect F Struct Biol Cryst Commun. 64: 641-644.
214.Jin T, Albillos SM, Chen YW, Kothary MH, Fu TJ, Zhang YZ (2008). Purification and characterization of the 7S vicilin from Korean pine (Pinus koraiensis). J Agric Food Chem. 56: 8159-8165.
215.Albillos SM, Jin T, Howard A, Zhang Y, Kothary MH, Fu TJ (2008). Purification, crystallization and preliminary X-ray characterization of prunin-1, a major component of the almond (Prunus dulcis) allergen amandin. J Agric Food Chem. 56: 5352-5358.
216.Jin T, Kim S, Guo F, Howard A, Zhang YZ (2007). Purification and crystallization of recombinant human TNF-like ligand TL1A. Cytokine. 40: 115-122.
217.Jin T, Howard A, Zhang YZ (2007). Purification, crystallization and initial crystallographic characterization of peanut major allergen Ara h 3. Acta Crystallogr Sect F Struct Biol Cryst Commun. 63: 848-851.
218.Jin T, Guo F, Serebriiskii IG, Howard A, Zhang YZ (2007). A 1.55 A resolution X-ray crystal structure of HEF2/ERH and insights into its transcriptional and cell-cycle interaction networks. Proteins. 68: 427-437.
219.Jin T, Guo F, Kim S, Howard A, Zhang YZ (2007). X-ray crystal structure of TNF ligand family member TL1A at 2.1A. Biochem Biophys Res Commun. 364: 1-6.
220.Jin T, Fu TJ, Kothary MH, Howard A, Zhang YZ (2007). Crystallization and initial crystallographic characterization of a vicilin-type seed storage protein from Pinus koraiensis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 63: 1041-1043.
221.Guo F, Jin T, Howard A, Zhang YZ (2007). Purification, crystallization and initial crystallographic characterization of brazil-nut allergen Ber e 2. Acta Crystallogr Sect F Struct Biol Cryst Commun. 63: 976-979.
222.Wu X, Wei H, Jin T, Tian Z (2007). Ag85B induces the antitumor immunity effect. China J. Lepr Skin Dis. 23(1): 6-9.
223.Jin T, Guo F, Wang Y, Zhang YZ (2006). Identification of human dim1 as a peptidase with autocleavage activity. Chem Biol Drug Des. 68: 266-272.
224.Jin T, Howard AJ, Golemis EA, Wang Y, Zhang YZ (2005). Overproduction, purification, crystallization and preliminary X-ray diffraction studies of the human spliceosomal protein TXNL4B. Acta Crystallogr Sect F Struct Biol Cryst Commun. 61: 282-284.
225.Jin T, Howard A, Golemis EA, Wang Y, Zhang YZ (2005). Overproduction, purification, crystallization and preliminary X-ray diffraction studies of the human transcription repressor ERH. Acta Crystallogr Sect F Struct Biol Cryst Commun. 61: 531-533.
226.吴学忠, 魏海明, 郑晓东, 金腾川, 田志刚(2007). 结核杆菌抗原Ag85B诱导抗黑素瘤免疫应答及其机制研究[J].细胞与分子免疫学杂志,(01):36-38.
227.吴学忠, 魏海明, 金腾川, 田志刚(2007). Ag85B诱发抗肿瘤免疫效应[J].中国麻风皮肤病杂志,(01):10-11.
228.金腾川, 张瑞军, 魏海明, 何海辉, 田志刚(2004). 重组人白细胞介素-18的高浓度复性、纯化和活性检测[J].中国生化药物杂志,(02):67-71.
专利申请
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国家发明专利，专利名称：腺相关病毒介导的新型冠状病毒抗体诱导物及疫苗组合物；发明人：薛天，金腾川，才源，章梅，童大力；专利申请号：2020109031439 ；2022.09.09授权；
国家发明专利，专利名称：与SARS-CoV-2 RBD结合的羊驼源纳米抗体；发明人：金腾川，马欢，曾威红；专利申请号：2020110381236，2023.06.16授权；
国家发明专利，专利名称：与SARS-CoV-2 RBD结合的羊驼源纳米抗体；发明人：金腾川，马欢，曾威红；专利申请号：2020110381240，2023.06.16授权；
国家发明专利，专利名称：与SARS-CoV-2 RBD结合的羊驼源纳米抗体；发明人：金腾川，马欢，曾威红；专利申请号：2020110375841，2023.06.16授权；
国家发明专利，专利名称：与SARS-CoV-2 RBD结合的羊驼源纳米抗体 ；发明人：金腾川，马欢，曾威红；专利申请号：2020110373511；2021.03.01授权；
国家发明专利，专利名称：与SARS-CoV-2 RBD结合的羊驼源纳米抗体 ；发明人：金腾川，马欢，曾威红；专利申请号：2020110374266 ；2022.05.03授权；
国家发明专利，专利名称：一种髓鞘少突胶质细胞糖蛋白抗体试剂盒及其检测方法；发明人：余旭亮，金腾川，郝洪军；专利申请号： 202011524431X，2022.07.22授权；
国家发明专利，专利名称：一种微流控芯片；发明人：金腾川，丁卫平，成斌，李清宁；专利申请号：202011574296X ；2023.02.17授权；
国家发明专利，专利名称：结合人RAGE胞外域的羊驼源抗体；发明人：金腾川，艾哈迈德·穆罕默德；专利申请号：2021104753819，2022.12.06授权；
国家发明专利，专利名称：包含陀螺样本微量离心装置的纸基微流体芯片检测系统及其应用；发明人：李博峰，金腾川，巩凡吾，魏华兴；专利申请号：2021105562058，2023.08.22授权；
国家发明专利，专利名称：特异性表达人源性单克隆中和抗体的B细胞的制备方法及应用，发明人：高勇，谢佳佳，丁承超，张玉清，,刘志荣，金腾川，何军，张思平；专利申请号：2023109985686；
国家发明专利，专利名称：一种用于抗原检测的复合材料和试剂盒；发明人：崔华,王珊珊,金腾川；专利申请号：2021107123303，2023.03.10授权；
国家发明专利，专利名称：新型冠状病毒CD8+ T细胞表位肽及其用途；发明人：金腾川，谭旭，邓莎莎，张航； 专利申请号：202110927606X，2023.08.29授权；
国家发明专利，专利名称：一种靶向SARS-CoV-2RBD蛋白的鲨源纳米抗体和应用；发明人：陈玉磊，林锦锦，曹敏杰，金腾川；专利申请号：2023109983144；
国家发明专利，专利名称： 靶向SARS-CoV-2RBD蛋白的鲨源纳米抗体、制备方法和应用；发明人：陈玉磊，林锦锦，曹敏杰，金腾川； 专利申请号：2022101043013，2024.02.13授权；
国家发明专利，专利名称：绿色荧光蛋白鲨源纳米抗体、制备方法及其应用；发明人：陈玉磊，解鑫鑫，曹敏杰，金腾川，谢仰杰，马欢；专利申请号：2022101042701，2023.09.01授权；
国家发明专利，专利名称：靶向SARS-CoV-2RBD蛋白的鲨源纳米抗体和应用；发明人：陈玉磊，林锦锦，曹敏杰，金腾川；专利申请号：2023109983182；
国家发明专利，专利名称：与人血小板衍生生长因子受体β（PDGFRβ）结合的羊驼源纳米抗体；发明人：金腾川，王清清；专利申请号：2022101503981；2024.02.23授权；
国家发明专利，专利名称：广谱抗非典、新冠病毒及其突变株的纳米抗体aSA3；发明人：金腾川，马欢，曾威红，邱香果；专利申请号：202210758292X；
国家发明专利，专利名称：靶向IL-6Rα蛋白的纳米抗体及其用途；发明人：李博峰，金腾川，钱娇娇，魏华兴；专利申请号：2022113425682；
国家发明专利，专利名称：食物过敏原点刺液检测试剂盒的制备方法；发明人：尹大龙,金腾川，谢佳佳，束越，蒋法兴；专利申请号：2022116362702；
国家发明专利，专利名称：鸡蛋过敏原点刺液检测试剂盒制备方法；发明人：尹大龙，金腾川，谢佳佳，束越，蒋法兴；专利申请号：2023100650051；
国家发明专利，专利名称：牛奶过敏原点刺液检测试剂盒制备方法；发明人：尹大龙，金腾川，谢佳佳，束越，蒋法兴；专利申请号：2023101016805；
国家发明专利，专利名称：基于机器学习和单细胞转录图谱的肺腺癌诊断模型和预后模型；发明人：金腾川，程庆宇；专利申请号：2023102158080；
国家发明专利，专利名称：人源四聚体分泌型IgA2m2-Fc骨架及其在预防和治疗呼吸道病毒感染中的应用；发明人：金腾川，曾威红，马欢，邱香果；专利申请号：2023110659495；
国家发明专利，专利名称：结合小鼠SiglecE胞外域的羊驼源抗；发明人：金腾川，赵丹；专利申请号： 2023112083451；
国家发明专利，专利名称：一种靶向FcεRIα蛋白胞外段的纳米抗体及其应用；发明人：金腾川，黄晓雪；专利申请号：2023113714691；
国家发明专利，专利名称：结合人免疫球蛋白E（IgE）的羊驼源纳米抗体；发明人：金腾川，朱利霞；专利申请号：2023114303757；
国家发明专利，专利名称：一种LED模拟控制的小球藻培养装置及方法；发明人：邹家莉，王汉春，张昕昱，刘志鹏，姚程炳，刘文，金腾川；专利申请号：2023115137379；
国家发明专利，专利名称：与人PD-1结合的羊驼源双特异性抗体；发明人：金腾川，马欢；专利申请号：2024104259080；
国家发明专利，专利名称：与人PD-L1结合的羊驼源双特异性抗体；发明人：金腾川，马欢；专利申请号：2024104258980 ；
国家发明专利，专利名称：广谱中和埃博拉病毒的骆驼源抗体；发明人：金腾川，王美华，邱香果，李恩涛；专利申请号：2024107595717；
国家发明专利，专利名称：广谱中和埃博拉病毒的骆驼源抗体；发明人：金腾川，王美华，邱香果，李恩涛；专利申请号：2024107595702 ；
国家发明专利，专利名称：一种新型冠状病毒亚单位抗原及其应用；发明人：金腾川，杨芸茹；专利申请号： 2024108198531；
国家发明专利，专利名称：一种新型冠状病毒长多肽抗原及其应用；发明人：金腾川，杨芸茹；专利申请号：2024108199712；
国家发明专利，专利名称：一种新型冠状病毒重组亚单位抗原及其制备方法和应用；发明人：金腾川,杨芸茹；专利申请号：2024108196150；
国家发明专利，专利名称：一种提高亚单位疫苗体液免疫水平的IL-21融合蛋白及其制备方法；发明人：李博峰,邓真存,魏华兴,金腾川；专利申请号：2024110916249；
国家发明专利，专利名称：结合人免疫球蛋白 E 的骆驼源纳米抗体；发明人：金腾川，朱利霞；专利申请号：2024116741746
国家发明专利，专利名称：结合人免疫球蛋白 E 的骆驼源纳米抗体；发明人：金腾川，朱利霞；专利申请号：2024116741712
国家发明专利，专利名称：一种靶向 FcεRIα 蛋白胞外段的纳米抗体 antiFcεRIa-D11 及其应用；发明人：金腾川，黄晓雪，专利申请号：2024117168253
国家发明专利，专利名称：一种靶向 FcεRIα 蛋白胞外段的纳米抗体 antiFcεRIa-E11 及其应用；发明人：金腾川，黄晓雪，专利申请号：2024117168215；
计算机软件著作权，专利名称：基因组测序数据分析流程软件V1.0；著作权人：金腾川,程庆宇,张雅馨；2025.04.29颁证；
国家实用新型专利，专利名称：一种SPR传感芯片及其镀膜装置；发明人：金腾川，丁丽秀；专利申请号：2025206838529；
国家发明专利，专利名称：靶向单纯疱疹病毒的纳米抗体 Nb14 及其应用；发明人：金腾川，胡婧；专利申请号：202410476944X；
国家发明专利，专利名称：靶向单纯疱疹病毒的纳米抗体 Nb32 及其应用；发明人：金腾川，胡婧；专利申请号：202410476856X；
国家发明专利，专利名称：一种靶向狂犬病毒的纳米抗体aRV7及其应用；发明人：金腾川，姚靖雪；专利申请号：2025109784578；
国家发明专利，专利名称：一种靶向狂犬病毒的纳米抗体aRV15及其应用；发明人：金腾川，姚靖雪；专利申请号：2025109784563；
国家发明专利，专利名称：一种靶向狂犬病毒的纳米抗体aRV29及其应用；发明人：金腾川，姚靖雪；专利申请号：2025109784544；
国家发明专利，专利名称：一种靶向狂犬病毒的纳米抗体aRV48及其应用；发明人：金腾川，姚靖雪；专利申请号：202510978453X；
国家发明专利，专利名称：一种靶向Siglec-9的纳米抗体及其应用；发明人：金腾川，路曼晴；专利申请号：2025109784525；
国家发明专利，专利名称：一种靶向SLAMF7的纳米抗体及其应用；发明人：金腾川，郑培义；专利申请号：2025109999762；
国家发明专利，专利名称：一种突变型链球菌蛋白G及其在马血清F(ab')2纯化中的应用；发明人：尚玉花、姚程炳、金腾川；专利申请号：2025112471901；
国家发明专利，专利名称：酶联斑点的识别计数方法、装置和电子设备；发明人：彭杰，金腾川，吴艾久，王宇晴，谢鑫，肖有为，方鹏旺，宋绍方，沈明亮，付忠谦；专利申请号：2025100732332。
承担项目：
实验室网页： http://tjlab.ustc.edu.cn
http://www.webofscience.com/wos/author/record/[B-5883-2014]
https://orcid.org/0000-0002-1395-188X
